- "While the appearance of a Tibetan wolf may be alarming, Kyrati residents can take comfort in the knowledge they will only meet one if they have been placed under arrest. Any other mention of encounters, such as those in the wild, are false."
- — In-game description
Tibetan Wolves are featured in the story, using the same purpose as animals in Far Cry 3, to get skins in order to craft equipment.
The wolves like to attack in packs to overwhelm the player. To deal with a large mass of them, kill the pack leader (this wolf is usually darker than the others), the other wolves will scatter.
Although usually found in packs, occasionally a wolf can be seen on its own. Even a lone wolf is a force to be reckoned with. Whenever summoned by bait only one wolf appears at a time. Sometimes wolves can have death duels with Clouded and Snow Leopards. One on one, the leopard usually wins. But against a pack, the leopard will either run off or be killed.
- Despite having more health and doing slightly more damage than Dholes, as well as being rarer (in the south at least), their hides are of around half the value of those of Dholes.