- "Face it. A buffalo is a cow, and pretty chill in general. They’re protective of their young and work together for protection. Then Mother Nature jams their heehaw full of radioactive goo. Was she having a bad hair day, or maybe she wanted to make a Spider-Cow? What? What would possess her to screw around with the cud-chewing hippies of the animal kingdom?"
- — Data Console
The Mutant Buffalo is an animal in Far Cry 3 Blood Dragon.